Search results for "Clinical applications"
showing 8 items of 8 documents
Engineered Membranes for Residual Cell Trapping on Microfluidic Blood Plasma Separation Systems: A Comparison between Porous and Nanofibrous Membranes
2021
Blood-based clinical diagnostics require challenging limit-of-detection for low abundance, circulating molecules in plasma. Micro-scale blood plasma separation (BPS) has achieved remarkable results in terms of plasma yield or purity, but rarely achieving both at the same time. Here, we proposed the first use of electrospun polylactic-acid (PLA) membranes as filters to remove residual cell population from continuous hydrodynamic-BPS devices. The membranes hydrophilicity was improved by adopting a wet chemistry approach via surface aminolysis as demonstrated through Fourier Transform Infrared Spectroscopy and Water Contact Angle analysis. The usability of PLA-membranes was assessed through de…
Editorial: Breakthrough BCI Applications in Medicine
2020
Resinas compuestas: Revisión de los materiales e indicaciones clínicas
2006
El objetivo de este trabajo es presentar los diferentes componentes de los composites actualmente utilizados en Odontología y aportar al profesional las bases que puedan proporcionarle los criterios a tener en cuenta para seleccionar uno u otro en función de los requerimientos terapéuticos. La mayoría de los composites de uso en Odontología corresponden a materiales híbridos, se denominan así por estar conformados por grupos poliméricos reforzados por una fase inorgánica de vidrio de diferente composición, tamaño y porcentaje de relleno. Los composites fluidos o los condensables han tratado de dar respuesta algunos requerimientos funcionales, aunque sin demasiado éxito en la mejora de sus p…
Biomateriālu: Biodentīna un Minerāltrioksīda agregāta (MTA) izmantošana zobārstniecībā anonīmā aptauja
2020
Ievads: Šī pētījuma mērķis bija noskaidrot, kādu biomateriālu, MTA vai Biodentīnu ikdienā izmanto zobārsti Latvijā un kādi ir faktori to nosaka. Metodes: Šķērsgriezuma pētījums tika veikts starp zobārstniecības speciālistiem, kuri strādā dažādu Latvijas Republikas reģionu klīnikās. Anketa tika izveidota, lai iegūtu nepieciešamo informāciju par MTA un Biodentīna izmantošanu konservatīvajā zobārstniecībā un endodontijā. Pētījumu apstiprināja Latvijas Universitātes Kardioloģijas un reģeneratīvās medicīnas institūta zinātniskās izpētes ētikas komisija. Rezultāti: No respondentiem tika saņemtas 105 aizpildītas anketas, kuras arī tika iekļautas datu analīzē. Respondenti bija vispārējie zobārsti (…
Breast cancer proteomics: from research to clinical applications.
2008
The exponentially increasing volume of information extracted from genomic and proteomic applications on cancer, while providing new insights into molecular composition of cancer cells and tissues, imposes new challenges on data rationalization as a tool for clinically relevant biomarker discovery. Breast cancer represents the most frequent and potentially aggressive type of cancer and, moreover, it is one of the most enigmatic and poorly predictable in its evolution, likely because it includes several different forms that behave differently among patients. Current clinical parameters for breast cancer diagnosis and cure are: tumour size, axillary lymph node status, histological grading and …
Health Education at La Ribera Universitary Hospital
2013
This paper describes the potential of learning platforms offering at the La Ribera Health Department. More than 100 activities have been designed and at least 5000 users have been participating. The paper concludes, first, that there are important factors to achieve a successful implementation of such elearning project. In second place it remarks that elearning platform can be used for other support activities rather than only online courses. Finally, the study emphasizes that training in electronic medical record of our professionals is a key element of hospital business.
Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats
2019
Abstract Endocannabinoids (eCBs) and serotonin (5-HT) play a neuromodulatory role in the central nervous system. Both eCBs and 5-HT regulate neuronal excitability and their pharmacological potentiation has been shown to control seizures in pre-clinical and human studies. Compelling evidence indicates that eCB and 5-HT systems interact to modulate several physiological and pathological brain functions, such as food intake, pain, drug addiction, depression, and anxiety. Nevertheless, there is no evidence of an eCB/5-HT interaction in experimental and human epilepsies, including status epilepticus (SE). Here, we performed video-EEG recording in behaving rats treated with the pro-convulsant age…
New advances in radiomics of gastrointestinal stromal tumors
2020
Gastrointestinal stromal tumors (GISTs) are uncommon neoplasms of the gastrointestinal tract with peculiar clinical, genetic, and imaging characteristics. Preoperative knowledge of risk stratification and mutational status is crucial to guide the appropriate patients' treatment. Predicting the clinical behavior and biological aggressiveness of GISTs based on conventional computed tomography (CT) and magnetic resonance imaging (MRI) evaluation is challenging, unless the lesions have already metastasized at the time of diagnosis. Radiomics is emerging as a promising tool for the quantification of lesion heterogeneity on radiological images, extracting additional data that cannot be assessed b…